Gout can involve the ankle joint and cause pain on the inside of the ankle joint, which can be accompanied by local skin redness and swelling, increased skin temperature, and the formation of gout stones in serious cases. Second, ligament injury, of course, when there is a sprain of the medial collateral ligament of the ankle joint, there can be pain in the medial ligament of the ankle joint, there can be obvious pressure pain, limitation of ankle joint movement, swelling of the ankle joint, early examination and, if necessary, an MRI of the ankle joint should be taken for early diagnosis. Third, tendinitis, when inflammation of the posterior tendon of the medial ankle joint occurs, there can also be pain in the posterior aspect of the medial ankle joint, early physical examination should be conducted to diagnose, and if necessary, closed treatment.