Early symptoms of osteomyelitis are characterized by redness, swelling, heat and pain in the skin and muscles around the joints, formation of sinus tracts, and oozing from wounds. Osteomyelitis is an infection and destruction of bone tissue, usually occurring in the knee joint. Early manifestations of osteomyelitis are localized pain, redness and swelling of the joints and increased local skin temperature. Sometimes there are also systemic symptoms, such as fatigue, loss of appetite, fever, chills and so on. In addition, sinus tracts, wound exudate is also a clear manifestation of osteomyelitis, wound exudate is usually clear liquid. If the above symptoms occur when, suggest the possibility of osteomyelitis. At this time, you need to go to the orthopedic department of the hospital in a timely manner, combined with imaging tests to help determine. After determining the early stage of osteomyelitis, the main thing is to carry out antibiotic treatment, such as the use of penicillin, erythromycin, etc., but also rest and braking, the appropriate use of magnesium sulfate topical application to help control the inflammation.