The serotypes covered by domestic and imported 13-valent pneumonia vaccine are the same, the difference is that the domestic vaccine is applicable to infants and children from 6 weeks of age to before 6 years of age, and the price is lower, while the imported 13-valent pneumonia vaccine is applicable to infants and children from 6 weeks of age to 15 months of age, and the price is higher. Domestic and imported thirteen-valent pneumonia vaccine covers the same pneumococcal serotypes, including 1, 3, 4, 5, 6A, 6B, 7F, 9V, 14, 18C, 19A, 19F, and 23F, a total of 13 serotypes, and the production process of the two is also the same, the complete inoculation needs to be vaccinated with 4 doses, and there is no difference in immunization effect between the two. The difference between domestic and imported 13-valent pneumonia vaccine mainly lies in the recommended vaccination age, imported 13-valent pneumonia vaccine is applicable to infants and young children from 6 weeks to 15 months of age; while the two domestic 13-valent pneumonia vaccines are applicable to infants and young children from 6 weeks to 6 years of age, and the price of the domestic vaccine is slightly lower, so the domestic 13-valent vaccination program is more flexible.