Calcified foci of hepatic s2 are calcified spots found by ultrasound within the upper left outer lobe of the liver, which are usually bile salts that precipitate and thus form a foreign body present in the body and can stimulate hyperplasia of the surrounding nodular tissue. The liver is divided into 8 segments in hepatobiliary surgery, with segment s2 being the upper left outer lobe. Calcified foci are a pathological change that occurs after a liver disease has been stabilized or healed, and they persist after their occurrence. Clinically, the foci do not disappear or develop on their own. Since the foci are relatively small, they generally have no adverse effects on the body. Secondly, hepatic s2 calcified foci may suggest that the patient has a disease such as cholestasis or purulent cholangitis, so the patient’s hepatic s2 calcified foci are diagnosed through ultrasound examination and follow-up observation. The diagnosis of hepatic s2 calcification foci usually does not require treatment, but if the diagnosis of related hepatobiliary diseases need to be standardized treatment.