Obesity – beware of diabetes

  The incidence of diabetes is increasing year by year, obesity is the biggest risk factor of diabetes, China in 80-81 years in 14 provinces and cities on 304,537 people census found 1,854 cases of diabetes, the standardized prevalence rate of 6.74 ‰, and Daqing survey data show that an average of about 6-7% of low glucose tolerance will develop into diabetes each year. In turn, there is a very close relationship between body weight and the rate of development of diabetes. The prevalence of diabetes is 20.4‰ among 40,630 people in the overweight group, of which the prevalence of diabetes is extremely low in the group under 20 years old, and increases significantly with age above 40 years old, reaching a peak at 60-70 years old. In the United States, a survey of 755,000 people found that 85% of diabetics were obese, and among those who were obese, those who were severely obese were four times more likely to develop diabetes than those who were mildly obese. 70%-80% of diabetics over the age of 40 had a history of obesity. Obesity starts with normal fasting blood glucose, and sometimes there is a hypoglycemic response 3-4 hours after eating, which is the result of delayed insulin secretion. As the history of obesity lengthens, glucose tolerance decreases, starting with high postprandial glucose, followed by an increase in fasting glucose, which eventually leads to diabetes if beta-cell function is low or defective.  Diabetes is an endocrine disorder characterized by high blood sugar and urine sugar. At present, there are at least 94 million diabetic patients in China, and obesity is the biggest harmful factor of diabetes. Obese people have abnormal insulin metabolism in their bodies and produce insulin resistance, which reduces the transfer of glucose to tissue cells on the one hand and increases the production of glucose in the liver on the other, thus leading to an increase in blood glucose. The World Health Organization Obesity Society calls for obesity to be treated as a disease in its own right, and the increase in the number of obese people has affected the health services of entire countries. The scope and severity of obesity is now one of the biggest health problems on par with smoking. Some sources indicate that the health risks of obesity are four times higher than those of smoking. Obesity has become a major contributor to many non-communicable diseases and can lead to diseases such as diabetes. Recent studies have concluded that: high fat content in the human body leads to obesity, obesity predisposes to diabetes, and the key to its prevention and control is to control fat rather than sugar. Richard Thweatt, a professor of psychiatry at Duke University, said, “We have a lot of research to do. Thweatt said: “We experimented with rats that were bred and made to suffer from type 2 diabetes, and the results showed that a strict low-fat diet could better control the development of diabetes, and some rats were even cured”.  Professor Thweatt said, “It is wrong for doctors or patients to see sugar as the main cause of diabetes, and it is a pure waste of time to try to control diabetes with a low-sugar diet. However, if a diabetic patient sticks to a low-fat diet and reduces fat intake to a lower level, for example by reducing the calories provided by fat intake from 40 to 10 percent, diabetes is better controlled”. Therefore, it is important for diabetic patients with obesity to take non-pharmacological measures such as weight loss and low-calorie, low-fat diet control (balanced diet) while taking glucose-lowering medications. Weight loss can reduce the size of enlarged beta cells, increase insulin sensitivity, improve glucose tolerance, significantly reduce blood glucose concentration, and increase the number of insulin receptors.  Diet control is preferred in the treatment of obese patients Diet control is not simply treated as starvation therapy, but requires a balanced diet. The core of it is to pay attention to the quality and quantity of the diet. The quality is the structure of the diet and the quantity is the total calories of the diet. The purpose is 1 to maintain normal life, labor, study and other normal activities; 2 to maintain normal body weight, and the wasting type patients are appropriately increased to maintain body weight close to the standard range; 3 to reduce the burden on pancreatic beta cells. By appropriately restricting diet, we can avoid over-stimulating insulin secretion by pancreatic β-cells. Simple starvation therapy, on the other hand, does not achieve the above-mentioned therapeutic goals.  Secondly, behavior modification therapy depends on the individual situation of the patient. Firstly, patients should make a detailed diary of their life, especially the dietary record, including the quantity of food eaten, the type of food, the place of eating, the degree of hunger before eating, the speed of eating, the number of chewing, the feeling when stopping eating, the arrangement of three meals a day, as well as the habit of snacking, the type of snack and the habit of eating under irritability and exertion. Thereafter, the records were analyzed specifically to identify any problems. Patients were asked to make daily diet records and to measure their weight after waking up, after breakfast, after dinner and before sleep daily to enhance self-monitoring.  Thirdly, physical exercise is second only to diet control in terms of importance. Physical activity leads to a reduction in body fat, but not all physical activities of the same nature have the same effect. Activities characterized by aerobic metabolism, such as jogging, fast walking (115-125 steps/min), gymnastics, swimming, mountain climbing and tai chi, etc., can cause sympathetic excitation and a decrease in plasma insulin. And increased secretion of several theophyllamines, glucagon and growth hormone promote lipolysis.  In short, the treatment of obesity must be individualized. First of all, we should let patients understand the harm of obesity disease, clarify the purpose of weight loss, establish confidence, set a realistic weight loss goal, based on diet control, with behavior correction therapy and physical exercise, supplemented by drug therapy if necessary, and persevere in order to achieve better weight loss results. Through weight loss, the body load can be effectively reduced and the internal environment of the body can be improved, which helps control and treat diabetes. Therefore, we should pay attention to the treatment of obesity, reduce the incidence of obesity, and improve the health of our people!