Lung cancer of 17cm is still serious, and it is difficult to perform surgical resection clinically. Lung cancer is a relatively common disease in clinic, once it reaches 17cm, it means that the lesion is often accompanied by localized situation, so it is locally advanced stage, which is often difficult to be completely resected, and the risk of surgery is very high. For this kind of patients, radiotherapy, chemotherapy, targeted therapy and other treatments can be considered, especially in recent years, targeted therapy, for some patients compared with radiotherapy, chemotherapy can achieve better therapeutic effects, and the adverse effects are relatively mild, so patients need to take pathological biopsy for genetic testing to assess whether they are sensitive to targeted therapy and what kind of targeted drugs. Since it is inoperable, it is difficult to be completely cured. Therefore, lung cancer 17cm is still serious and needs active radiotherapy, chemotherapy and targeted therapy, but it is difficult to perform surgical resection.