The soft tissue density shadow in the area of duodenal horizontal section is mostly considered to be the existence of edema, inflammation, tumor and other lesions in the local soft tissue, which can be seen in duodenal ulcer, duodenal varicose vein and other diseases. Usually, soft tissue density shadow belongs to the CT examination results of professional expression, duodenum horizontal section of regional soft tissue density shadow means that through the examination of the duodenum horizontal part of the duodenum there may be edema, inflammation, tumors and other lesions, for doctors to diagnose the disease to provide a strong basis. Generally, in the clinic, it is mostly seen in duodenal ulcer, duodenal varicose vein, duodenal cancer and other diseases. In addition, at this time, it is also necessary to do acoustic imaging, enhanced CT or enhanced MRI and other related tests, so that doctors can further diagnose or identify the disease. In conclusion, when the patient detects the presence of soft tissue density shadow in the horizontal segment of the duodenum, it is necessary to cooperate with the doctor to complete a series of related examinations to clarify the specific causes.