Whether to take medication for life after thyroid surgery depends on the extent of thyroidectomy and thyroid function, the specific situation needs to be specifically analyzed according to the surgical plan, and if hypothyroidism occurs after surgery, medication is needed. 1. Simple thyroid nodule removal surgery does not affect thyroid function, and lifelong medication is generally not required after surgery. 2. Lobectomy of the thyroid gland, if hypothyroidism occurs after the operation, thyroid hormone supplementation is needed to maintain the thyroid function in the normal range, if the thyroid function is normal after the operation, no medication is needed. 3. With total thyroidectomy, the thyroid function is usually completely lost, resulting in a complete lack of thyroid hormones in the body. Lifelong administration of thyroid hormone, such as levothyroxine sodium tablets, is required after surgery to maintain the body’s metabolism through exogenous supplementation of thyroid hormone. Whether or not to take medication for life after thyroid surgery depends on the specific condition and the treatment as prescribed by the doctor.