Dorem, i.e., proestrol tablets, may be used to increase the fertility preservation effect and prevent other risks if the doctor instructs to take the drug during the in vitro fertilization stage. Proestrol tablets are commonly used drugs in clinic, according to the analysis of its composition, it is mainly a simple progestin, and its effect is better than progesterone, which can increase the endocrine activity of placental trophoblast and promote the secretion of endogenous progesterone and HCG, which can stimulate the poorly functioning placenta and normalize the function of the placenta. Therefore, if it is necessary to take proestrol tablets during IVF transplantation, it may be to prevent the occurrence of risks such as preeclampsia, habitual abortion and preterm labor, and to protect the fetus. It is worth noting that the drug should be taken under the supervision of a doctor for proper use and should not be used on its own to avoid other serious problems. Women should start taking oral folic acid from 3 months before the planned pregnancy to prevent neural tube defects; if the vaccination should be done during the preparation for pregnancy, try not to vaccinate during pregnancy.