Cranial defects caused by various reasons are very common in clinical practice, and it has become a consensus among patients that cranial defects should be repaired and shaped. Before the surgery, many patients will think, “Is cranial repair surgery a minor surgery? As a matter of fact, cranial repair is a common brain surgery for repairing cranial defects caused by traumatic brain injuries and craniotomies, which cannot be said to be a minor surgery. However, one thing is certain, cranial bone repair surgery for plastic and neurological function recovery has a very obvious effect on the patient’s psychological, spiritual, rehabilitation will have a great impact, coupled with the cranial bone repair surgery in neurosurgery has been quite mature, can be done with confidence. The development of science and technology is ever-changing, and our medical and health care has also gained tremendous progress. Patients’ choice of cranial bone repair materials has also gradually become more specialized and advanced. Because it is the repair of cranial tissue, the choice of material first requires a high degree of biocompatibility, but also need to have a certain degree of strength and hardness, not only to provide strong enough to protect, but also to meet the needs of intraoperative plastic, to achieve the appearance of repair and cosmetic surgery to achieve satisfactory results. Currently used polyether ether ketone PEEK material is very good to achieve the patient’s needs, PEEK material has very good histocompatibility, basically will not produce rejection; PEEK material is based on the patient’s cranial CT data for three-dimensional molding, highly restored cranial physiological structure; PEEK cranial bone is embedded repair, so that the appearance of the repaired cranial bone is smooth, and will not produce a titanium mesh like the covering type of repair brought cutting injuries; PEEK cranial bone is embedded repair, so that the repaired cranial bone exterior smooth, will not produce like titanium mesh covering type of repair. PEEK material is embedded repair, so that the appearance of the repaired skull is smooth, and will not produce cutting damage like titanium mesh covered repair; PEEK material has good ray transmittance, which does not affect various medical examinations after the operation; In addition, PEEK material is comparable to human skull in elasticity, strength, heat insulation, stability, etc., and it is a very ideal cranial bone repair material.