Coughing for a few days at night is particularly severe may be reflux esophagitis, chronic pharyngitis, cough variant asthma, etc., can be treated by general treatment, drugs (omeprazole, compound borax solution, beclomethasone, etc.), physical, surgical and other methods. 1. Reflux esophagitis: This disease needs to be considered when patients experience symptoms such as acid reflux. Daily attention should be paid to reduce the factors causing increased intra-abdominal pressure, such as constipation, etc. At the same time, it is necessary to stop drinking and smoking, and it can be treated by drugs, such as omeprazole, ranitidine, mosapride, etc. Surgery can also be used to treat the disease, such as laparoscopic fundoplication. 2. Chronic pharyngolaryngitis: If the indoor environment is dry at night, it can stimulate the throat and cause cough aggravation, which can be treated by general treatment, such as humidifying the environment and drinking more water, and can be treated by medication, such as compound borax solution and iodine throat tablets, etc. Physical therapy, such as laser and low temperature plasma methods, can also be used. 3. Cough variant asthma: the disease is mainly related to genetic and environmental factors, aggravated at night or in the early morning, dry cough is the main, can be treated with medication, commonly used drugs, including beclomethasone inhaler, budesonide formoterol powder inhaler, and oral prednisone, if necessary. Serious cough at night, may also be caused by post-nasal drip syndrome, heart failure and other diseases, such as cough symptoms repeated bad or aggravated, it is recommended that the patient promptly go to the hospital, in the doctor’s diagnosis, combined with the patient’s specific condition, to take targeted treatment.