Miller syndrome refers to Miller-Fisher syndrome. Miller-Fisher syndrome is a subtype of Guillain-Barré syndrome, an acute multiple demyelinating neurogenic neuroinflammatory disease due to autoimmune dysfunction. Miller-Fisher syndrome can develop at any age and season. There may be a history of antecedent infections such as diarrhea and respiratory infections. The main manifestation is paralysis of the ocular muscles, and in some populations, facial muscle paralysis and ataxia may occur. Patients often start with diplopia, but may also start with myalgia, numbness of the limbs, vertigo and ataxia. Symmetrical or asymmetrical paralysis of the extraocular muscles may occur, some patients have ptosis, and a few have dilated pupils, but the pupil light reflex is usually normal. There may be ataxia of the trunk or limbs, and some have weakness of the swallowing and facial muscles, numbness and hyperalgesia of the distal extremities and face, and bladder dysfunction. The diagnosis of Miller-Fisher syndrome is often followed by treatment with high doses of gammaglobulin. If diagnosed with this disease, it is recommended to seek medical treatment as soon as possible, standardized diagnosis and treatment under the guidance of a professional physician, and actively cooperate with the doctor’s treatment, so as not to delay the disease.