Uremia is the final outcome of the continued progression of various chronic kidney diseases, and it is generally difficult to return to normal, only to control the progression of the disease. Patients with uremia have severely impaired renal function and often suffer from water, electrolyte and acid-base balance disorders, cardiovascular symptoms such as hypertension and left ventricular hypertrophy, gastrointestinal symptoms such as nausea and vomiting and taste of urine in the mouth, and respiratory symptoms such as shortness of breath and pleural effusion. Uremia treatment to delay the progression of renal function, to prevent the deterioration of renal function, etc. as the main purpose, it is generally difficult to return to normal, should be timely renal replacement therapy, specifically including hemodialysis, peritoneal dialysis and kidney transplantation. Uremia patients should go to the hospital in time, under the guidance of professional physicians.