Vitamin A cream is generally harmful in terms of dry skin, skin flushing and stinging. 1. Dry skin: retinoic acid cream will lead to moulting after use, generally caused by retinoic acid, this substance has anti-inflammatory, reduce sebaceous gland secretion, keratolysis, etc., so when used externally, there will be dry skin, moulting and other symptoms. 2. Skin flushing: Vitamin A cream has the function of anti-proliferative and anti-keratinization, which has a certain damage to the stratum corneum and has a certain sensitivity to light, so it will cause skin flushing. 3. Tingling: Due to the damage of the skin barrier, the stimulation of retinoic acid cream will cause skin tingling and itching. It is recommended that patients use retinoic acid cream under medical supervision to avoid adverse reactions.