Spots on the face may be caused by melasma, freckles, seborrheic keratosis and other diseases, which may be related to changes in the level of sex hormones, light exposure, skin aging and other factors. 1. Melasma: Melasma may be related to changes in sex hormone levels, mainly estrogen and progesterone. If estrogen is elevated in the body, it may stimulate melanin cells to secrete melanin particles, while progesterone will cause brown pigment particles to spread, resulting in chloasma on the face. 2. Freckles: Freckles have certain genetic susceptibility, if parents have freckles on their face, the chances of freckles appearing on the face of the next generation will increase, in addition, excessive exposure to light will also induce freckles. 3. Seborrheic keratosis: With the aging of skin, seborrheic keratosis will gradually appear and increase. Secondly, if genetic mutation occurs in the body, such as mutation of fibroblast factor, it may also lead to seborrheic keratosis on the face. There are many reasons for spots on the face, so it is recommended to go to a regular hospital for examination and clarification of the cause of the disease.