Novel coronavirus may affect the sense of taste. In some patients infected with novel coronavirus, the virus may invade the mucosal epithelial cells of the human respiratory tract, causing localized congestion and swelling of the mucosal epithelial cells, or localized increase in secretions that may block the lumen of the tubes, resulting in a reduced sense of smell or loss of the sense of smell. At the same time, the novel coronavirus may destroy the “support cells” of the auxiliary sensory neurons in the nose, resulting in the loss of the senses of smell and taste. In some patients with new coronavirus, the first symptom is loss of smell or taste. However, loss of smell and taste is not unique to CKP and cannot be diagnosed on the basis of this symptom alone. The diagnosis of C. neoformans requires a combination of epidemiologic history, nucleic acid test results, and imaging data. If there is a history of suspected exposure and an abnormal sense of smell or taste, nucleic acid testing should be performed promptly. Tip: In this article, the terms “neocoronavirus pneumonia” and “new coronavirus pneumonia” were renamed to “new coronavirus infection” on December 26, 2022, as announced by the National Health Commission.