In the past, the term “sexual impotence” in men was generally referred to as “impotence”, which was scientifically inaccurate and had a discriminatory and derogatory meaning. Until 1992, the U.S. National Institutes of Health, after discussion with relevant experts, decided to use the term erectile dysfunction (ED) instead of impotence, and defined penile erectile dysfunction as: persistent inability of the penis to achieve and/or maintain an erection sufficient to obtain a satisfactory sexual life (sexual intercourse). 1, psychosexual treatment As most patients with erectile dysfunction have psychological factors, so psychotherapy is very necessary, it is best to participate in psychosexual treatment with both husband and wife. Sexual concentration training is currently the most important treatment method for psychological erectile dysfunction, applicable to the treatment of almost all sexual dysfunction, the purpose of which is to relieve anxiety, improve communication and communication between the couple, improve the skills from verbal communication to non-verbal communication, and gradually improve the relationship and sexual function of the couple. The improvement rate of the method for erectile dysfunction is 20% to 81%. 2.Medication Oral medication is the simplest and most acceptable first-line treatment method in erectile dysfunction treatment. (1) Non-hormonal drugs: They can be roughly divided into the following categories according to the site of drug action. (1) Oral drugs acting on the central system such as adrenoceptor antagonists; dopamines; 5-hydroxytryptamine receptor antagonists. ② Oral drugs acting in the periphery PDE5 inhibitors (such as sildenafil, tadalafil, vardenafil, etc.) are specific phosphodiesterase inhibitors that inhibit cGMP degradation and increase cGMP concentration, thereby relaxing smooth muscle and causing penile erection. This class of drugs is currently the drug of choice for the treatment of ED, with an overall efficiency of more than 70%. (3) Topical drugs creams and ointments are the oldest methods in the treatment of erectile dysfunction, but the effect is not exact. (2) Hormonal drugs androgen replacement therapy: mainly used for the treatment of endocrine erectile dysfunction, including ED caused by primary and secondary hypogonadism. ① Primary hypogonadism testicular tumors, Creutzfeldt-Jakob syndrome, trauma, surgery and other lesions can lead to a decrease in testosterone levels and an increase in FSH and LH levels in the body, such patients have the best effect with exogenous testosterone replacement therapy. Secondary hypogonadism is caused by hypothalamic and pituitary lesions. The lack of gonadotropin causes stagnation of gonadal development, and the levels of testosterone, FSH and LH are reduced. After supplementation with gonadotropin or gonadotropin-releasing hormone, libido can be increased and erectile function can be improved. 3.Vacuum constriction device (VCD) The vacuum constriction device (VCD) can be used for erectile dysfunction of any cause and is a second-line method for treating ED. However, the hemodynamics that cause erection are different from those of a normal erection, and it does not have active relaxation of the cavernous body and smooth muscle. Animal tests have shown that arterial blood flow is not increased with VCD, but venous return is significantly reduced, and blood filling of the cavernous body and penile skin leads to penile enlargement. 4.Cavernous body injection therapy (ICI) Intracavernous drug injection is the injection of vasodilating drugs into the cavernous body of the penis to fill the cavernous body with blood for the purpose of penile erection. At present, the most commonly used drugs for cavernosal injection to treat erectile dysfunction are poppy bases, phentolamine and prostaglandin E1, etc. The method has obvious effect and fast onset of action. With the widespread use of oral drugs, the method is less and less used in clinical practice because it is an invasive operation and has side effects such as causing pain, bleeding, abnormal penile erection and penile fibrosis. 5, surgical treatment With the introduction of new drugs and the increased understanding of the pathogenesis of erectile dysfunction, surgical treatment is gradually reduced, but there are still some patients with erectile dysfunction need surgery to solve, generally by various other treatments are ineffective. Surgical treatments include prosthetic implants, revascularization, and venous ligation.