Painkillers is a general term for a class of drugs, if it is aspirin, you can take it 3 times a day, if it is Tramadol, you can take it 2 times a day, the maximum dose of 24 hours does not exceed 400mg, there is a variability in the dosage of specific drugs. Painkillers are drugs that can completely relieve or partially relieve pain, is a general term for a large class of drugs, therefore, to determine how many times a day painkillers can be taken, need to be based on the specific type of drug, can not be generalized. In general, if you are referring to aspirin, you can usually take it 3 times a day. If it refers to Tramadol, it can usually be taken twice a day, with the maximum 24-hour dose not exceeding 400mg. However, due to the patient’s condition as well as the drug manufacturers, specifications and other factors, so the specific dosage of the drug there is obvious individual variability. Secondly, some patients taking painkillers may experience adverse reactions such as nausea, vomiting, abdominal pain, etc. If they are allergic to the drug, they should avoid taking it. To summarize, patients must take painkillers under the guidance of a doctor, do not self-medication, so as not to delay the condition and affect the therapeutic effect.