A severe toothache cannot be controlled by taking one ibuprofen capsule, it can be taken again after 4~6 hours, but it is not recommended to take two capsules in a single dose. 1. Ibuprofen belongs to non-steroidal anti-inflammatory drugs, ibuprofen capsules are divided into ordinary capsules and slow-release capsules. Ordinary capsule specifications for 200mg / capsule, the pain continues to be unrelieved can be repeated at intervals of 4-6 hours, not more than 4 times in 24 hours. Extended-release capsules are 300mg/capsule, with a maximum of two capsules in 24 hours. 2. Two capsules of both sizes are not recommended to be taken at the same time. Increasing the dosage does not increase the efficacy of the medication, but may increase the side effects. Ibuprofen is contraindicated in case of drug allergy, such as those who have ever been allergic to aspirin, pregnancy, breastfeeding and other conditions prohibit the use of the drug. Adverse reactions such as nausea, vomiting, gastrointestinal ulcers and bleeding, headache, rash, etc. after the use of the drug, it is recommended to stop the drug and consult a doctor. Toothache can not be relieved, only by ibuprofen and other pain medication, can not be treated fundamentally, it is recommended to go to the hospital on the possible causes of the disease, such as dental caries, pulpitis, etc. to relieve the pain, you need to comply with the doctor’s instructions for the use of medication.