Two itchy calves, may be related to eczema, pruritus, atopic dermatitis and other reasons, need to be specifically analyzed according to clinical symptoms. 1. Eczema: it occurs in the hands, feet, calves and other places, mostly symmetrical distribution, clinical acute lesions to herpes mound, with a tendency to ooze, chronic to moss-like changes, easy to recur, often conscious of itching. 2. Pruritus: Dry weather can lead to rapid water loss in the body, resulting in skin dehydration, usually manifested as no primary rash, but there are symptoms of itching. 3. Atopic dermatitis: lesions often manifested as limited mossy changes, sometimes acute, subacute eczema-like changes, some patients lesions manifested as generalized dry papules, itching intense. The cause of the two calf itch more reasons, it is recommended to go to the hospital in a timely manner, a clear cause, under the guidance of the doctor for standardized treatment, so as not to delay the condition.