Spots on the sides of nose and cheeks may be freckles, chloasma or nevus of Ota, which can be removed by medication, laser and other treatment measures. 1. Freckles: they can be congenital or acquired, attention should be paid to the sun protection of the skin, nowadays laser or IPL (Intense Pulsed Light) is commonly used in the treatment, and they can also be treated by chemical exfoliation (such as the use of Trichloroacetic Acid solution and phenol), but they are rarely used due to the possibility of pigmentation disorders or scarring. 2. Melasma: avoid sunlight exposure, use sunscreen on the face to reduce the formation of melasma; for the already formed spots, external decolorizing agents can be used, such as hydroquinone cream, azelaic acid cream or compound arbutin cream, etc.; systemic medication can be chosen from vitamin E, vitamin C and tranexamic acid, in addition, laser also has a certain therapeutic effect. 3. Nevus of Ota: also known as brownish-bronze nevus of the upper jaw of the eye, commonly used Q-switched wavelength of 694nm ruby laser, wavelength of 1064nm Nd: YAG laser, wavelength of 755nm emerald green gemstone laser treatment in order to achieve cosmetic treatment effect. For nose and cheek spots, if there is a need for treatment, you can go to a hospital specialist and choose the appropriate treatment measures to remove the lesions.