To remove fire from the heart, one can use Guan Chi San or Guan Chi Wan. The effect of Guan Chi San is to clear the heart, promote water retention and nourish the yin, which can be used to treat heart meridian fire-heat syndrome; while Guan Chi Wan has the effect of clearing heat and diarrhea, and diuretic and laxative. Therefore, both of them have the effect of removing heart fire, but which drug should be chosen to remove heart fire, it is still recommended to consult a doctor, the doctor will decide according to the condition. 1. Guiding Chi San, composed of Mutong, raw rhizome and other drugs. It has the efficacy of clearing the heart, inducing diuresis and nourishing yin, and is mainly used for the treatment of heart meridian fire-heat syndrome, which is characterized by irritation and heat in the heart and chest (irritability and sullenness), thirst and face redness, desire for cold drinks and sores on the mouth and tongue; or heart heat moving to the small intestine, with red, stinging pains in the urination, a red tongue, and a number of pulses, etc. The formula is bitter and cold. In the formula, Mutong is bitter and cold, and Shengdi is soft and cold, so it should be used with caution when the spleen and stomach are weak. 2. Guiding Red Pill, composed of Mutong, red peony, gardenia, poria and other drugs. It has the efficacy of clearing heat and diarrhea, diuretic and laxative, and is used for symptoms such as mouth and tongue sores caused by internal heat, sore throat, irritable heat in the heart and chest, short and red urine (small amount of urine, dark yellow color), constipation, etc. It is also used for the treatment of stomatitis, stomatitis, and other diseases. This medicine can be used in conjunction with external medicines when treating stomatitis and mouth ulcers.