With the popularity of cervical cancer screening, abnormalities in cytology are increasingly detected, which makes many patients nervous and even fearful, and they often ask me worriedly, “Dr. Chen, do I have cervical cancer?” In fact, cytology screening is mainly for screening out women with possible cervical precancer in the population, and there is a set of standard for the diagnosis and management of cervical precancer. The most commonly used cervical cancer screening tests are cervical cytology (TCT/CCT/LCT) and HPV testing. Some of the 2012 American Society for Colposcopy and Cervical Pathology (ASCCP) treatment guidelines are now briefly described. If the cervical cytology test (TCT/CCT/LCT) is reported as atypical squamous epithelial cells of uncertain significance (ASC-US), then the following options are available to everyone: 1. HPV testing is preferred (for women ≥30 years of age). If HPV is positive, colposcopy will be performed; if negative, TCT and HPV will be repeated in 3 years. 2. It is also optional to repeat TCT after 12 months, especially in women aged 21-24 years. If the TCT is still abnormal after the review, colposcopy will be performed; if it is negative, TCT will be repeated after 3 years. 3. Direct colposcopy is not recommended.