Management of cervical cytologic and histologic abnormalities according to ACOG clinical guidelines. The low likelihood of cancer in adolescents and the long window for detecting persistent high-grade precancerous lesions make immediate excision inappropriate. Colposcopic biopsy of visible lesions is the recommended primary treatment option . If the colposcopic findings are satisfactory, the cervical canal is negative and no lesions are found, or the biopsy is suggestive of CIN1 or no tumor, a series of cervical smears and colposcopies at 6-month intervals for 2 years is recommended. Routine annual screening may be continued if 2 consecutive cervical smears and colposcopies are negative. Biopsy is recommended if high-grade colposcopic lesions are identified at follow-up or if HSIL cytology findings persist for 1 year. If HSIL persists for 2 years, a diagnostic hysterectomy is recommended. Adolescent and young women may return to routine screening if two consecutive negative cytologic scrapings and no high-grade colposcopic abnormalities are present.