Ankylosing spondylitis with deformed waist may be caused by ankylosing spondylitis resulting in deformation of the spine, which needs to be treated by medication or surgical correction. Ankylosing spondylitis patients with the progression of the disease, the spine in the lumbar, thoracic, cervical vertebrae will be violated and gradually deformed, the spine of patients with advanced stage will be due to the fusion of vertebrae and other reasons for the formation of a hard arch, ankylosing spondylitis patients with medication, commonly used therapeutic drugs such as LiuZiSulphon pyridine, adalimumab, and so on. The above medications must be taken as prescribed by the doctor. Drugs can play a role in slowing down the progress of the patient’s condition and relieving the patient’s symptoms, but for patients with spinal deformity need to undergo surgery to correct the treatment, and spinal correction surgery through the implantation of a brace in the patient’s body, the patient’s deformed spine straighten and maintain, can play a role in reducing the patient’s spinal deformity, and to maintain the effect of the balance of the torso. The specific treatment plan for patients with ankylosing spondylitis should be formulated by professional doctors according to the patients’ conditions. It is recommended that patients with ankylosing spondylitis should go to the rheumatology and orthopedics department of regular hospitals in time after the occurrence of lumbar deformity to avoid delaying their conditions.