Glycated antigen 125 test result of 39.18u/mL is recommended to be retested, and imaging and pathologic tests can be performed to clarify the lesion if necessary. The normal reference range for serum Glycoantigen 125 is <35u/mL, so 39.18u/mL is a mild elevation, and retesting may be an option due to possible errors in the test. Elevation of GAC 125 can be seen in malignant diseases such as ovarian tumor, cervical cancer, pancreatic cancer, biliary tract cancer, liver cancer, etc. It can also be seen in physiological state, early pregnancy, benign ovarian tumor, uterine fibroids, liver cirrhosis. Therefore, if necessary, it is recommended to carry out CT and other imaging and pathologic examinations to clarify the nature of the disease, and adopt targeted treatment such as surgery and medication. It is recommended to consult a doctor as soon as possible for standardized diagnosis and treatment.