The five-year survival rate of stage 2 sigmoid colon cancer is between 60% and 70% after treatment, and the specific number of years of survival can vary. Sigmoid colon cancer is an intestinal malignant tumor caused by various factors such as gene mutation, bad dietary habits, etc. Stage 2 staging is relatively early, representing a variety of conditions such as the tumor grows through the intrinsic muscle layer to the subplasma membrane; no lymph node metastasis; no distant metastasis. The lesions in this period are relatively more limited and milder. In stage 2 sigmoid colon cancer, it can mostly be treated by radical surgical resection, and then supplemented with radiotherapy and chemotherapy according to the condition after surgery. After active treatment, the prognosis is relatively good, and the five-year survival rate is about 60%~70%. It is necessary to pay attention to the postoperative period to follow the doctor’s instructions for regular review, maintain good living habits, positive and optimistic with the treatment, improve the quality of life, is expected to achieve a five-year survival rate of clinical healing.