Common hazards and side effects of Fenomotone, generically known as Estradiol Tablets/Estradiol Dydrogesterone Tablets, include headache, abdominal pain, breast tenderness, vaginal bleeding, malaise, and vaginal bleeding. Estradiol Tablets/Estradiol Dydrogesterone Tablets are sex hormones and reproductive system regulators, clinically used for perimenopausal syndrome due to natural or postoperative menopause. Some patients may experience central nervous system symptoms such as headache, dizziness and migraine after using the drug, and the symptoms usually disappear on their own after stopping the drug, or gastrointestinal discomfort such as nausea, abdominal pain and gastrointestinal flatulence may occur. A small number of patients may also develop reproductive system and breast disease, common symptoms include breast swelling and pain, vaginal bleeding, cervical secretion changes in the nature and amount of symptoms. In addition, other patients may develop allergic skin reactions such as rash and itching, and systemic symptoms such as fatigue. During the medication period, once serious and persistent discomfort symptoms occur, consult a doctor for targeted treatment. Estradiol Tablets/Estradiol Dydrogesterone Tablets are prescription drugs, strictly follow the doctor’s instructions on dosage and usage, do not blindly self-medication, in order to avoid the emergence of serious harm and side effects.