Several hypoechoic nodules refer to the discovery of multiple substantial masses during ultrasound examination, which is commonly found in breast nodules, thyroid nodules or lipomas. 1. Breast nodules: mostly related to endocrine hormone disorders, environment, infection, emotions and other reasons. Several hypoechoic nodules may be detected during physical examination, mammography, or ultrasound. 2. Thyroid nodules: Most of them are caused by iodine deficiency, degenerative changes, obesity, heredity and other factors. Several hypoechoic nodules may be found during ultrasound examination of the thyroid gland. Thyroid nodule puncture biopsy and other tests can confirm the nature of the nodule. 3. Lipoma: It is mostly caused by the abnormality of the tumorigenic factor of lipoma, which will make the normal adipose tissue proliferate to form lipoma. It is mainly manifested as lumps on the surface of the body, not accompanied by special symptoms, and some patients may have pain. Several hypoechoes can be detected by ultrasound. It is recommended to go to the hospital in time to have the cause clarified by the doctor and to have the doctor standardize the treatment.