The time from stage 3 to stage 4 of renal failure is related to many factors such as the condition and treatment effect, and cannot be generalized. Kidney failure, i.e. chronic kidney disease, is the end-stage manifestation of various kidney diseases, which can be clinically categorized into 5 stages, stage 3 is a mild to severe decline in glomerular filtration rate, glomerular filtration rate between 30% and 59%; stage 4 glomerular filtration rate is severely reduced, glomerular filtration rate between 15% and 29%. If the patient is in the early stage of chronic kidney disease stage 3, the condition is mild, and after active treatment, the progress of chronic kidney disease can be effectively delayed, at this time, it can be slower to develop into chronic kidney disease stage 4; if the patient’s condition is more serious, the treatment effect is not good, it may be faster to develop into chronic kidney disease stage 4, but the specific time can not be generalized. Patients with chronic kidney disease are advised to go to regular hospitals in time and receive standardized treatment under the guidance of doctors.