The life expectancy of patients with organ failure is related to the organ that is failing, the severity of the failure, the speed of onset, whether or not the organ is effectively treated, and whether or not the underlying lesion that caused the organ failure and the cause of the disease are resolved, so there are individual differences in survival time. In the case of acute pulmonary failure due to pulmonary embolism or acute heart failure due to infection, the organ function of most patients can be restored to normal after timely and effective treatment, which does not affect the patient’s life expectancy at this time. In the case of multiple organ failure due to massive trauma or bleeding, the patient’s mortality rate will increase, and some patients may even die on the same day. In case of chronic failure of a single organ, the organ function can usually be maintained by drugs or machines. If the symptoms are not severe and well controlled, there is no effect on normal life expectancy at this time; if the organ failure is severe and poorly controlled, the patient’s life expectancy will be seriously affected, and the survival time will even be less than one year. Patients with organ failure should be treated for the cause of the disease as early as possible to control the condition early to avoid an irreversible situation.