The main antihypertensive drugs that can increase the heart rate are calcium channel antagonists, such as diphenhydramine and amlodipine, which will reflexively increase the heart rate due to the lowering of blood pressure, and other antihypertensive drugs such as verapamil and diltiazem, which will cause the heart rate to slow down, and many antihypertensive drugs such as the beta-blocker colistin, which will also slow down the heart rate. drugs such as valsartan or ACEI captopril do not affect the heart rate, but a sudden decrease in blood pressure can also reflexively cause the heart rate to increase. Patients who have a fast heart rate can choose beta-blockers such as metoprolol and bisoprolol, while patients with a slow heart rate can choose nifedipine for antihypertensive treatment.