Metoclopramide tablets are antiemetic, dopamine D2 receptor antagonists, and also have 5-hydroxytryptamine 4th receptor agonist effects and mild inhibition of 5-HT3 receptors. Side effects of metoclopramide tablets include irritability, fatigue and weakness, breast swelling and pain, nausea, constipation, diarrhea, poor sleep, dizziness, thirst, headache, and moodiness. Metoclopramide tablets are mainly used for the treatment of nausea and vomiting, belching, indigestion, flatulence, hyperacidity and other symptoms caused by various etiologies; reflux esophagitis, bile reflux gastritis, functional gastric retention, gastric ptosis, etc.; delayed gastrointestinal emptying; diabetic gastro-hypoparalysis, diabetes mellitus, scleroderma, and other collagen disorders caused by obstruction of gastric emptying. Long-term administration of large doses may lead to extrapyramidal reactions due to blockade of dopamine receptors, resulting in adverse effects such as myoclonus, dysphonia, and ataxia. It is contraindicated in those who are allergic to procaine or procainamide, gastrointestinal bleeding, mechanical intestinal obstruction or perforation, pheochromocytoma, pregnant patients, and breast cancer patients who vomit due to chemotherapy and radiotherapy. Long-term use is not recommended for the elderly and children. Nursing women should be cautious of using it, and patients with liver failure should be cautious of using it. If you need to use metoclopramide tablets, please consult a professional doctor, follow the doctor’s instruction and use the medicine reasonably.