Small liver function and large liver function mainly refer to the difference in the number of examination items, that is, compared with small liver function, large liver function examination items are more comprehensive and detailed, and can more fully reflect the synthesis, metabolism, transformation, excretion and other related functions of the liver. There are some differences in the specific items of large liver function and small liver function tests in different hospitals, generally the items of small liver function tests mainly include transaminases, bilirubin, albumin and so on. In addition to the above-mentioned indexes, the major liver function examination items also include total protein, prealbumin, globulin, albumin-globulin ratio, glutamyl-glutamic acid ratio, glutamyl transpeptidase, alkaline phosphatase, cholinesterase, total bile acids, adenosine deaminase, sialic acid, glutamate dehydrogenase, etc. For example, for people with a history of liver disease or those who need to undergo surgery related to the liver and biliary system, a more comprehensive major liver function test is required.