Artificial prosthesis pacemaker is a kind of medical electronic instrument, which can regularly issue electrical impulses to simulate the impulse formation and conduction of the normal heart, and is used in the diagnosis and treatment of some cardiovascular diseases and the experimental research of cardiac electrophysiology. 1.For diagnosis (1) Atrial pacing to assist in the diagnosis of suspected coronary heart disease. (2)Atrial overdrive pacing is used to diagnose sinus node insufficiency. (3) To predict the risk of heart-brain syndrome in patients with complete AV block. 2. For treatment (1) Single-chamber pacemaker: To restore normal heart rhythm by timely pacing of the ventricle or atrium according to the need of the ventricular or atrial rate. (2) Dual-chamber pacemaker: Provides sequential atrial and ventricular pacing to treat sick sinus node syndrome with normal atrial and ventricular function. (3)Triple-chamber pacemaker: to coordinate atrial and interventricular activities, to improve cardiac function, and to treat intractable heart failure and certain dilated cardiomyopathies. 3. For cardiac electrophysiology experimental research: the improvement of the function of the artificial prosthesis pacemaker has gradually revealed some difficult to explain electrophysiological phenomena, and has played a positive role in the research of cardiac electrophysiology. The clinical application of artificial prosthesis pacemaker is more extensive, and there will be its corresponding complications after using, should follow the doctor’s instructions for regular follow-up observation.