Headache from time to time, generally without organic lesions may be caused by mental tension, stress or lack of sleep, or may be caused by fluctuations in blood pressure, which may cause headache when high, and the patient’s headache symptoms will be relieved if the blood pressure is normal. Therefore, for patients with high blood pressure, blood pressure lowering drugs must be preferred to long-acting preparations to make the patient’s blood pressure as stable as possible. If the blood pressure is unstable for a long time, it may also damage the inner lining of the blood vessels, which may cause atherosclerosis, cerebral infarction or cerebral hemorrhage, and the drugs commonly used in clinical practice are levoclodipine, amlodipine besylate, irbesartan, valsartan, and also nifedipine extended-release tablets, nifedipine controlled-release tablets or candesartan for treatment. It may also occur if the patient has a history of cervical spine disease.