Pituitary enlargement should be analyzed specifically, some of the pituitary enlargement belongs to physiological enlargement, in puberty or pregnancy women may have physiological pituitary enlargement, without special treatment. To exclude the possibility of physiological enlargement, it is necessary to suspect whether the patient has a common tumor of the pituitary gland. At present, pituitary tumor as a kind of benign tumor, the treatment effect is better. With the development of neurosurgical technology, pituitary tumors can be resected by transnasal microscopic and endoscopic surgery for tumor removal without craniotomy, which is less traumatic and quicker recovery for patients. Some tumors with aggressive growth may not be cured by surgical treatment, and may have to be combined with medication and radiation therapy after surgery, but the prognosis is relatively poor. The prognosis for patients diagnosed with pituitary tumors with enlarged pituitary gland is relatively good.