A lot of small particles around the lips, consider with perioral dermatitis, acne related. 1. Perioral dermatitis: Perioral dermatitis is inflammatory skin that occurs around the mouth and nose, the cause of which has not been fully clarified. It is mainly characterized by erythema, papules and scales on the upper lip, nasolabial folds, nose and chin, sometimes causing moderate itching or burning sensation. 2. Acne: It is a kind of skin lesion manifestation of acne, which is related to factors such as high androgen level and abnormal keratinization of follicle sebaceous gland ducts. Acne occurs on the forehead, cheeks, chin, etc., resulting in localized conical-shaped pimples that are consistent with skin color. A lot of small particles appear around the lips, it is recommended to go to the dermatology department of the hospital, to clarify the cause, under the guidance of the doctor for treatment.