Immunoglobulins are globulins that have the activity or chemical substance of antibodies and are similar to antibody molecules. In contrast, albumin is synthesized by the liver parenchyma and has a half-life of about 15-19 days in plasma, making it the most abundant protein in plasma. The immune system is made up of immune tissues and organs, immune cells, and immune active molecules. Albumin is a negative ion and can carry more than 200 negative charges per molecule, making it a very major carrier in plasma. Many poorly water-soluble substances can be transported by binding to albumin. These substances include bilirubin, long-chain fatty acids, prostaglandins, steroid hormones, and metal ions. One of the roles of immunoglobulins is their role in preventing and preventing the further spread of infection. In turn, albumin is decisive for maintaining circulating blood volume, maintaining blood pressure and circulating perfusion.