Abdominal masses need to be judged by a combination of history, symptoms, physical examination, laboratory tests, imaging, and pathologic biopsy. 1. Medical history, such as liver and gallbladder diseases, appendicitis, megasplenism, colorectal polyps and so on, is of great significance to the diagnosis. 2. Symptoms: Different abdominal masses have different symptoms, which are of great significance to the diagnosis. For example, right upper abdominal pain with poor appetite, anorexia, etc., mostly consider liver and gallbladder system mass; lower abdominal mass with abdominal pain, mostly consider colon mass. 3. Physical examination: the diagnosis can be made by touching the site of the mass, smoothness, activity, size, pressure and pain, etc. Common benign masses include lipoma, mesenteric cyst, gallbladder effusion, etc. Common malignant masses include colorectal cancer, gastric cancer, etc. 4. Laboratory examination: blood, urine and stool routine, blood and urine biochemistry, tumor antigen detection and other examinations are of great significance to the diagnosis. 5. Imaging examination: ultrasound, abdominal plain film, CT (including enhancement), MRI and other examinations are commonly used. 6. Pathologic biopsy: through puncture, surgical excision of specimens, can be a clear diagnosis. The diagnosis of abdominal mass requires comprehensive judgment and cannot be based on one factor alone.