The septal thickness of 12mm is basically normal, the septal thickness is related to gender and age, the normal septal thickness range for men is 6.9-11.7mm, the normal range for women is 5.5-10.7mm, the septal thickness of 12mm is slightly thicker, usually does not cause clinical symptoms, and can be reviewed regularly. If it continues to thicken, it is hypertrophic cardiomyopathy, which is divided into two categories: obstructive and non-obstructive according to the presence or absence of obstruction in the left ventricular outflow tract. Non-obstructive is less severe than obstructive hypertrophic cardiomyopathy, and there are no symptoms in the early stage, and septal hypertrophy is not obvious, only slightly less endurance than others when exercising. The main risk is sudden exercise death, once diagnosed you can not continue to do strenuous exercise, if chest tightness, shortness of breath can take metoprolol, myocardial hypertrophy continues to increase can do alcohol ablation.