With the continuous improvement of people’s living standards, the popularization of medical and health knowledge, as well as the reform of the publicly funded medical system, many families are equipped with daily medication to meet minor illnesses and injuries self-medication, both convenient and timely, but also affordable. In order to ensure the safety and effectiveness of medication should pay attention to several issues: 1, to prevent drug abuse. Abuse of drugs is regardless of the condition, the object of medication (elderly, adults, children), drug performance and arbitrary use, this practice is ineffective in the light, prolonging the treatment time, the serious delay in treatment to aggravate the condition, bringing pain to the patient. 2, as little as possible to combine drugs. Some drugs used in combination play an additive role, so as to improve the efficacy; some drugs used in combination play a subtractive role, so that the efficacy is reduced, or increased toxicity. Therefore, it is best to use the family medicine single product or two drugs used in combination is sufficient. 3, according to the drug instructions, you can not ignore the drug packaging precautions, measuring the use of a drug, not just look at its use and purpose, for non-professional family members, its precautions are more important, it is a guarantee of safe and effective use of drugs. 4, to prevent drug allergies. Anyone who is allergic, or has a history of drug allergies in the past, taking drugs should be extra careful, especially sulfonamides such as cotrimoxazole, antipyretic and analgesic painkillers such as painkillers. Those who have a clear history of allergy to certain drugs in the past should be prohibited from using them again.