High thyroglobulin antibodies and thyroid peroxidase can be seen in Hashimoto’s thyroiditis, Graves’ disease, etc. Hashimoto’s thyroiditis without thyroid function abnormality usually does not need treatment, hypothyroidism can be used for levothyroxine sodium tablets; Graves’ disease can be treated with medication, radioactive iodine therapy, and surgical treatment. 1. Hashimoto’s thyroiditis: Hashimoto’s thyroiditis is a kind of autoimmune thyroiditis, only thyroglobulin antibody and peroxidase antibody are high without thyroid function abnormality generally do not need to be treated; combined with hypothyroidism, levothyroxine sodium tablets should be given to replace the treatment. 2. Graves’ disease: Graves’ disease not only has high thyroglobulin antibody and peroxidase antibody, but also has high thyrotropin receptor antibody, which is often manifested as hyperthyroidism, and it needs to limit iodine intake, and it can be treated with methimazole, propylthiouracil antithyroid therapy, radioactive iodine therapy, and surgical treatment. Thyroglobulin antibodies and peroxidase antibodies are both high, you should go to the hospital, to clarify the cause, under the guidance of the doctor treatment.