Genital herpes can be spread through sexual intercourse without skin lesions. Genital herpes is a sexually transmitted disease caused by herpes simplex virus infection, which causes skin damage to the urogenital and perianal skin mucosa. Infection with the herpes simplex virus is contagious regardless of whether the body has skin damage, and is mainly transmitted through sexual intercourse, but contact with the patient’s blister fluid, or household items contaminated by the patient, may also cause transmission. Genital herpes is also contagious through sexual intercourse without skin lesions, and is more likely to be contagious with skin lesions. Patients with genital herpes should go to the hospital for treatment as soon as possible, and keep the skin clean and hygienic, avoid sexual intercourse during the period of illness to prevent cross-infection.