Lower back pain after taking leukapheresis injection, which is also known as recombinant human granulocyte colony-stimulating factor, can be relieved through general treatment, physical therapy, medication and other ways. 1. General treatment: including lying down to rest, urinating and defecating in bed, changing clothes in bed and avoiding waist activities and weight bearing, which can alleviate the symptoms of low back pain in some of the people who have been injected with recombinant human granulocyte colony-stimulating factor. 2. Physical therapy: after injection of recombinant human granulocyte colony-stimulating factor, due to the massive proliferation of leukocytes in the bone marrow cavity oppression of the nearby bone, resulting in muscle pain, lumbago, so you can carry out the pain of localized hot compresses and other physical therapy to relieve. 3. Medication: When the pain is intolerable and affects sleep and life, medicines such as meloxicam and ibuprofen extended-release capsules can be applied to relieve the pain, or creams such as flurbiprofen gel paste can be used. It should be noted that, when back pain occurs after injection of recombinant human granulocyte colony-stimulating factor, the doctor should be notified in time, and under the guidance of the doctor for treatment or application of drugs.