Patients with Helicobacter pylori infection who suffer from abdominal pain: first, the cause of the disease should be clarified. Since Helicobacter pylori is one of the main culprits of many gastric diseases, the patient should undergo endoscopy in the hospital to clarify the basic condition of his/her stomach. If there is chronic gastritis, gastric ulcer or duodenal ulcer, the patient should be treated with acid-suppressing medication, gastric mucosa-protecting medication or gastric motility-promoting medication to relieve the abdominal pain. Secondly, the treatment of eradicating Helicobacter pylori is commonly used at present, which is quadruple therapy. In addition, if there is a malignant tumor in the stomach, treatment needs to be given according to the size and location of the stomach cancer.