Minimally invasive cholecystectomy to open laparotomy can be due to the occurrence of anatomical difficulties, intraoperative bleeding and injury, gallbladder cancer and other situations. 1. Anatomical difficulties: when performing laparoscopic cholecystectomy, if the gallbladder has severe inflammation, local tissue hyperplasia and adhesion, or anatomical variations, it is difficult to dissect and reveal important tissues such as gallbladder triangle, and the forced surgery may cause side injuries such as damage to the common bile duct, and the surgery needs to be transferred to open abdomen. 2. Intraoperative bleeding injury: during minimally invasive surgery of gallbladder, due to anatomical variations, tight tissue adhesion, tough inflammatory tissues, or operation errors, etc., bile duct injury, portal vein injury, etc., and uncontrollable bleeding may occur, and at this time, it is necessary to carry out the surgery in an open abdominal setting to stop bleeding or repair the injury in a timely manner. 3. Gallbladder cancer: during laparoscopic cholecystectomy, if the gallbladder is highly suspected to be cancerous and metastatic, and the intraoperative rapid freezing in cholecystectomy makes it clear that the gallbladder is cancerous, then it is necessary to carry out lymph node dissection and metastatic foci treatment in a timely manner. After minimally invasive cholecystectomy to open abdomen, one can consult the competent doctor about the condition and actively cooperate with the medical care to perform rehabilitation therapy after the operation, which will help the early recovery of the disease.