People with persistently elevated CA199 should go to the hospital for abdominal CT, abdominal ultrasound and other examinations in time to confirm the diagnosis and take the next step of treatment. CA199 belongs to one of the digestive tract tumor markers, CA199 continuous elevation may be caused by pancreatic cancer, in the early stage of pancreatic cancer, some patients may appear CA199 value is elevated, combined with CEA co-testing, both values are elevated, then it should be heavily suspected of pancreatic cancer, and it should be treated by surgery in time. Besides, elevated CA199 has some relationship with cholangiocarcinoma, rectal cancer, colon cancer, etc. Therefore, it should be further diagnosed through gastroscopy, colonoscopy, etc. If the patient is diagnosed as cancer, he/she should be treated through surgery, radiotherapy, etc., and it is recommended to consult the doctor in time.