Genital glands generally refer to male testicles and female ovaries. If there is pain in the genital glands, it is mainly considered to be caused by local trauma, inflammation, tumor and other reasons. 1. Male gonadal pain: generally refers to pain in the testicular region, which may be caused by E. coli, mumps virus and other infections of the reproductive tract, resulting in orchitis, epididymitis, etc. Due to inflammation stimulation of the testicles and epididymis, it can lead to testicular pain, which is often accompanied by enlarged testicles, as well as generalized symptoms of low-grade fever. It may also be due to other reasons such as testicular trauma and testicular torsion. 2. Female genital gland pain: usually refers to ovarian pain, which may be caused by ovarian cyst torsion, ovarian cancer and other diseases. Ovarian cyst torsion belongs to one kind of acute abdomen, which can cause localized severe pain due to sudden change of body position. Ovarian cancer is the result of a combination of many factors, and the patient will suffer from pain in the lower abdomen and abdominal distension due to the invasion of cancer cells. There are many causes of gonadal pain, it is suggested that patients should consult doctor in time to find out the cause of the disease, and give targeted treatment after the doctor clarifies the cause of the disease.