Diabetes effects vary by drug, pick carefully

In recent years, diabetes has become a highly prevalent disease, seriously jeopardizing people’s health. In fact, as long as you choose the right suitable drugs, diabetics can live a long life. What are the medications for diabetes? This is a question that many diabetics and their families are very concerned about. Diabetes is caused by genetic factors, immune dysfunction, microbial infections and their toxins, free radicals toxins, mental factors and so on a variety of disease-causing factors in the body leading to pancreatic islet hypofunction, insulin resistance and so on a series of metabolic disorders triggered by glucose, protein, fat, water and electrolytes and other syndromes, in recent years, diabetes has become a high-prevalence disease, seriously jeopardizing people’s physical health. In fact, as long as you choose the right drugs, diabetics can also live a long life. 1, sulfonylurea drugs This kind of drug belongs to the promotion of insulin secretion agent, mainly by increasing the secretion of insulin to reduce blood sugar. Commonly used drugs are glibenclamide (euglycemic), gliclazide (Damicam), glipizide (Disha tablets, mepida), gliquinone (glyburide), glimepiride (Wansupin, Yamoly) and so on. Mainly for non-obese patients with type 2 diabetes, the common adverse reaction is hypoglycemia, long-term users can appear weight gain. 2, biguanide drugs This kind of drug belongs to insulin sensitizer, mainly by reducing the output of liver glucose to reduce blood sugar. Commonly used drugs are metformin. Suitable for obese and overweight patients with type 2 diabetes mellitus, common adverse reactions are gastrointestinal reactions, occasional allergic reactions, in the case of hepatic and renal insufficiency, hypovolemic shock, cardiac failure and other hypoxic conditions can occasionally induce lactic acidosis, should be used with caution. 3, Glargine drugs These drugs belong to the insulin secretion agent, mainly by stimulating the early secretion of insulin phase to reduce postprandial blood glucose, characterized by fast absorption, fast onset of action, short duration of action. Commonly used drugs are Naglinide (Tangli), Repaglinide (Novaluron) and so on. The common adverse reaction is hypoglycemia. 4, α-glucosidase inhibitors These drugs are mainly through the inhibition of intestinal α-glucosidase and delay the absorption of carbohydrates, reduce postprandial hyperglycemia. Commonly used drugs include Acarbose (Bayerisepine, Carboplatin), Voglibose (Bexin) and so on. It is mainly applied to patients with predominantly postprandial hyperglycemia, and common adverse reactions include gastrointestinal reactions, such as abdominal distension, diarrhea, and excessive gas. 5, thiazolidinediones This kind of drug belongs to the insulin sensitizer, mainly through the improvement of insulin resistance, is the organization of insulin sensitivity increase and achieve the role of lowering sugar. Commonly used drugs are rosiglitazone (vindia, too Luo). It is mainly used in the early stage of diabetes and type 2 diabetes with a certain amount of presence in the body. Common adverse reactions include edema and weight gain, and it will lead to aggravation of heart failure in patients who already have heart failure, and it should not be used in patients with cardiac function grade III-IV. 6, enteric insulinotropic hormone, mainly to promote insulin secretion, inhibit pancreatic glucagon secretion, regulate the feeding center and other effects. It is a kind of glucagon like peptide drugs, also called human glucagon-like peptide-1 (GLP-1) analogs, such as: liraglutide, exenatide, etc.. It can control blood glucose and reduce body weight better. The main adverse effects are gastrointestinal reactions, nausea, vomiting and abdominal pain. 7.Dipeptidyl peptidase IV (DPP4) inhibitor DPP4 is a kind of enzyme in the body, also known as enzyme. Its main role is in breaking down proteins in the body! One of the proteins broken down by DPP4 is called GLP-1, which is a hormone secreted by intestinal cells. GLP-1 can lower blood glucose by stimulating insulin, inhibiting glucagon, inhibiting gastric emptying, and regenerating pancreatic islet cells. DPP4 inhibitors, which inactivate DPP4 and thus do not break down GLP-1, have become one of the main focuses of diabetes treatment. At present, the DPP4 inhibitors with the most in-depth research and have been applied to the clinic are selegiline, vigliptin and saxagliptin. 8, Chinese medicine Modern pharmacological research has proved that many single-flavored Chinese medicines have hypoglycemic effect. However, the treatment of diabetes in Chinese medicine, like the treatment of other diseases, is characterized by the importance of individual differences in patients and the use of compound prescriptions. TCM is characterized by multi-targets, multi-pathways and low adverse effects. The treatment of diabetes with TCM is not only about lowering blood glucose, but more importantly focuses on the prevention and treatment of diabetic complications, which serves to improve the quality of life and prolong life span. Compared with Chinese herbs, the application of proprietary Chinese medicines is more common, such as: hypoglycemic ning and thirst-quenching pills.